BLACK CURRANT – Uses, Side Effects, and More

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Carmen Ramirez-Tortosa, M., Garcia-Alonso, J., Luisa Vidal-Guevara, M., Quiles, J. L., Jesus, Periago M., Linde, J., Dolores, Mesa M., Ros, G., Abellan, P., and Gil, A. Oxidative stress status in an institutionalised elderly group after the intake of a phenolic-rich dessert. Br J Nutr 2004;91(6):943-950. View abstract.

Deferne, J. L. and Leeds, A. R. Resting blood pressure and cardiovascular reactivity to mental arithmetic in mild hypertensive males supplemented with blackcurrant seed oil. J.Hum.Hypertens. 1996;10(8):531-537. View abstract.

Diboune, M., Ferard, G., Ingenbleek, Y., Bourguignat, A., Spielmann, D., Scheppler-Roupert, C., Tulasne, P. A., Calon, B., Hasselmann, M., Sauder, P., and . Soybean oil, blackcurrant seed oil, medium-chain triglycerides, and plasma phospholipid fatty acids of stressed patients. Nutrition 1993;9(4):344-349. View abstract.

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Lengsfeld, C., Deters, A., Faller, G., and Hensel, A. High molecular weight polysaccharides from black currant seeds inhibit adhesion of Helicobacter pylori to human gastric mucosa. Planta Med. 2004;70(7):620-626. View abstract.

Leventhal, L. J., Boyce, E. G., and Zurier, R. B. Treatment of rheumatoid arthritis with blackcurrant seed oil. Br.J.Rheumatol. 1994;33(9):847-852. View abstract.

Matsumoto, H., Nakamura, Y., Hirayama, M., Yoshiki, Y., and Okubo, K. Antioxidant activity of black currant anthocyanin aglycons and their glycosides measured by chemiluminescence in a neutral pH region and in human plasma. J.Agric.Food Chem. 8-28-2002;50(18):5034-5037. View abstract.

Moller, P., Loft, S., Alfthan, G., and Freese, R. Oxidative DNA damage in circulating mononuclear blood cells after ingestion of blackcurrant juice or anthocyanin-rich drink. Mutat.Res. 7-13-2004;551(1-2):119-126. View abstract.

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Nielsen, I. L., Dragsted, L. O., Ravn-Haren, G., Freese, R., and Rasmussen, S. E. Absorption and excretion of black currant anthocyanins in humans and watanabe heritable hyperlipidemic rabbits. J.Agric.Food Chem. 4-23-2003;51(9):2813-2820. View abstract.

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Watson, J., Byars, M. L., McGill, P., and Kelman, A. W. Cytokine and prostaglandin production by monocytes of volunteers and rheumatoid arthritis patients treated with dietary supplements of blackcurrant seed oil. Br.J.Rheumatol. 1993;32(12):1055-1058. View abstract.

Young, J. F., Nielsen, S. E., Haraldsdottir, J., Daneshvar, B., Lauridsen, S. T., Knuthsen, P., Crozier, A., Sandstrom, B., and Dragsted, L. O. [Polyphenolic antioxidants in fruit juice. Urinary excretion and effects on biological markers for antioxidative status]. Ugeskr.Laeger 3-6-2000;162(10):1388-1392. View abstract.

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Bitsch I, Janssen M, Netzel M, et al. Bioavailability of anthocyanidin-3-glycosides following consumption of elderberry extract and blackcurrant juice. Int J Clin Pharmacol Ther 2004;42:293-300. View abstract.

Dalgård C, Nielsen F, Morrow JD, et al. Supplementation with orange and blackcurrant juice, but not vitamin E, improves inflammatory markers in patients with peripheral arterial disease. Br J Nutr 2009;101:263-9. View abstract.

De Luca P, D’Ascanio L, Cingolani C, et al. A Supplement with Ribes Nigrum, Boswellia Serrata, Bromelain and Vitamin D to Stop Local Inflammation in Chronic Sinusitis: A Case-Control Study. J Clin Med 2023;12(8):2929. View abstract.

Dejima K, Ohshima A, Yanai T, et al. Effects of polysaccharide derived from black currant on relieving clinical symptoms of Japanese cedar pollinosis: a randomized double-blind, placebo-controlled trial. Biosci Biotechnol Biochem 2007;71:3019-25. View abstract.

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Erlund I, Marniemi J, Hakala P, et al. Consumption of black currants, lingonberries and bilberries increases serum quercetin concentrations. Eur J Clin Nutr 2003;57:37-42. View abstract.

Fa-lin Z, Zhen-yu W, Yan H, et al. Efficacy of blackcurrant oil soft capsule, a Chinese herbal drug, in hyperlipidemia treatment. Phytother Res 2010;24 Suppl 2:S209-13. View abstract.

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Fryer S, Giles D, Bird E, et al. New Zealand blackcurrant extract enhances muscle oxygenation during repeated intermittent forearm muscle contractions in advanced and elite rock climbers. Eur J Sport Sci 2020 Nov 17:1-9. doi: 10.1080/17461391.2020.1827048. View abstract.

Furse RK, Rossetti RG, Seiler CM, Zurier RB. Oral administration of gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, modulates interleukin-1beta production by human monocytes. J Clin Immunol 2002;22:83-91. View abstract.

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Lappi J, Raninen K, Väkeväinen K, Kårlund A, Törrönen R, Kolehmainen M. Blackcurrant (Ribes nigrum) lowers sugar-induced postprandial glycaemia independently and in a product with fermented quinoa: a randomised crossover trial. Br J Nutr 2020 Nov 9:1-10. doi: 10.1017/S0007114520004468. View abstract.

Lyall KA, Hurst SM, Cooney J,et al. Short-term blackcurrant extract consumption modulates exercise-induced oxidative stress and lipopolysaccharide-stimulated inflammatory responses. Am J Physiol Regul Integr Comp Physiol 2009;297:R70-81. View abstract.

Matsumoto H, Takenami E, Iwasaki-Kurashige K, et al. Effects of blackcurrant anthocyanin intake on peripheral muscle circulation during typing work in humans. Eur J Appl Physiol 2005;94:36-45. View abstract.

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Menendez JA, Colomer R, Lupu R. Omega-6 polyunsaturated fatty acid gamma-linolenic acid (18:3n-6) is a selective estrogen-response modulator in human breast cancer cells: gamma-Linolenic acid antagonizes estrogen receptor-dependent transcriptional activity, transcriptionally represses estrogen receptor expression and synergistically enhances tamoxifen and ICI 182,780 (Faslodex) efficacy in human breast cancer cells. Int J Cancer 2004;10;109:949-54. View abstract.

Menendez JA, del Mar Barbacid M, Montero S, et al. Effects of gamma-linolenic acid and oleic acid on paclitaxel cytotoxicity in human breast cancer cells. Eur J Cancer 2001;37:402-13. View abstract.

Nanashima N, Horie K, Kitajima M, et al. Hypocholesterolemic Effect of Blackcurrant (Ribes nigrum) Extract in Healthy Female Subjects: A Pilot Study. Molecules 2021;26(13):4085. View abstract.

Nanashima N, Horie K, Maeda H, Tomisawa T, Kitajima M, Nakamura T. Blackcurrant Anthocyanins Increase the Levels of Collagen, Elastin, and Hyaluronic Acid in Human Skin Fibroblasts and Ovariectomized Rats. Nutrients. 2018;10(4). View abstract.

Ohguo H, Ohguro I, Yagi S. Effects of black currant anthocyanins on intraocular pressure in healthy volunteers and patients with glaucoma. J Ocul Pharmacol Ther 2013;29(1):61-7. View abstract.

Ohguru H, Ohguru I, Katai M, Tanaka S. Two-year randomized, placebo-controlled study of black currant anthocyanins on visual field in glaucoma. Ophthalmologica 2012;228:26-35. View abstract.

Puri BK. The safety of evening primrose oil in epilepsy. Prostaglandins Leukotrienes Essential Fatty Acids 2007;77:101-3.

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Röhrig T, Kirsch V, Schipp D, Galan J, Richling E. Absorption of anthocyanin rutinosides after consumption of a blackcurrant (Ribes nigrum L.) extract. J Agric Food Chem. 2019;67(24):6792-6797. View abstract.

Rose DP, Connolly JM, Liu XH. Effects of linoleic acid and gamma-linolenic acid on the growth and metastasis of a human breast cancer cell line in nude mice and on its growth and invasive capacity in vitro. Nutr Cancer 1995;24:33-45. . View abstract.

Rossi GCM, Scudeller L, Bettio F, Milano G. A Pilot, Phase II, Observational, Case-Control, 1-Month Study on Asthenopia in Video Terminal Operators without Dry Eye: Contrast Sensitivity and Quality of Life before and after the Oral Consumption of a Fixed Combination of Zinc, L-Carnitine, Extract of Elderberry, Currant and Extract of Eleutherococcus. Nutrients. 2021 Dec 13;13(12):4449. View abstract.

Somjorn P, Kamanamool N, Kanokrungsee S, Rojhirunsakool S, Udompataikul M. A cream containing linoleic acid, 5% dexpanthenol and ceramide in the treatment of atopic dermatitis. Asian Pac J Allergy Immunol 2021 Apr 18. doi: 10.12932/AP-230920-0969. View abstract.

Tahvonen RL, Schwab US, Linderborg KM, et al. Black currant seed oil and fish oil supplements differ in their effects on fatty acid profiles of plasma lipids, and concentrations of serum total and lipoprotein lipids, plasma glucose and insulin. J Nutr Biochem 2005;16:353-9. View abstract.

Traitler H, Winter H, Richli U, Ingenbleek Y. Characterization of gamma-linolenic acid in Ribes seed. Lipids 1984;19:923-8.. View abstract.

Vaddadi KS. The use of gamma-linolenic acid and linoleic acid to differentiate between temporal lobe epilepsy and schizophrenia. Prostaglandins Med 1981;6(4):375-379. View abstract.

Wu D, Meydani M, Leka LS, et al. Effect of dietary supplementation with black currant seed oil on the immune response of healthy elderly subjects. Am J Clin Nutr 1999;70:536-43. View abstract.

Yoshida K, Ohguro I, Ohguro H. Black currant anthocyanins normalized abnormal levels of serum concentrations of endothelin-1 in patients with glaucoma. J Ocul Pharmacol Ther 2013;29(5):480-7.View abstract.

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